Oxidative stress in epileptic patients on different antiepileptic monotherapy
نویسندگان
چکیده
منابع مشابه
Cognitive Functions in Epileptic Patients on Lamotrigine and Other Antiepileptic Drugs
Background and purpose: Anti-epileptic drugs (AEDs) can affect cognitive functions. The purpose of this study was to investigate the effects of lamotrigine (LT) on cognitive functions of patients with epilepsy. Materials and methods: A study with retrospective cohort design was carried out in which we assessed cognitive functions of 20 IGE patients attending Sari Bu Ali Hospital, and 12 health...
متن کاملPharmacovigilance in epileptic patients using antiepileptic drugs.
OBJECTIVE To investigate the occurrence of adverse effects of antiepileptic drugs (AED) in chronic epileptic patients in mono or polytherapy. METHOD We evaluated consecutive patients that met the following inclusion criteria: age of 18 years or older, diagnosis of epilepsy for at least one year, stable dose of AED for at least three months. Patients were asked if they had any adverse event re...
متن کاملHyperhomocysteinemia in epileptic patients on new antiepileptic drugs.
PURPOSE Older enzyme-inducing antiepileptic drugs (AEDs) may induce supraphysiologic plasma concentrations of total (t) homocysteine (Hcy). The aim of the present study was to investigate the effect of new AEDs on plasma tHcy levels. METHODS Patients 18-50 years of age, on AEDs monotherapy, with no other known cause of hyper-tHcy were enrolled. Plasma tHcy, folate, vitamin B(12), and AEDs lev...
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Background: Drug-induced epilepsy can be caused by certain medications and chemical agents. Oxidizing agents are among the chemical compounds that cause epilepsy. The aim of this study was to evaluate the anticonvulsant and antioxidant effects of amitriptyline on pentylenetetrazole (PTZ)-induced seizure in male rats. Materials and Methods: In this experimental study, 28 male Wistar rats (20...
متن کاملGastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients
Gastrointestinal (GI) discomforts are among the most common side effects of antiepileptic drugs (AEDs) that might lead to discontinuation or irregular consumption of the drugs. This study was conducted to evaluate the frequency of GI side effects of different AEDs in intractable epileptic patients treated with single or multiple drugs. GI discomfort of 100 epileptic patients (aged 35-76 years) ...
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ژورنال
عنوان ژورنال: Annals of the College of Medicine, Mosul
سال: 2007
ISSN: 2309-6217
DOI: 10.33899/mmed.2007.8835